Bo Ning

Interpretable machine learning model for predicting the ICU readmission of patients after coronary intervention

To develop and validate an interpretable machine learning (ML) model integrated with inflammatory indicators for predicting ICU readmission in patients after coronary intervention (PCI/CABG). We used retrospective data from MIMIC-IV (training, 2196 patients) and MIMIC-III (extern...

Identification of prognostic genes for hepatocellular carcinoma based on hepatocyte and ketone body metabolism using integrated bulk and single cell RNA sequencing

<title>Abstract</title> Background The precise role of ketone body (KB) metabolism and the underlying cellular mechanisms in hepatocellular carcinoma (HCC) remain unclear. This study aimed to identify and mechanistically explore KB metabolism-related prognostic genes in HCC. Meth...