Bin Guan

In vivo adaptive optics retinal imaging reveals rod-mediated cone photoreceptor disorganization in RHO-associated retinitis pigmentosa

Abstract Pathogenic variants in the rhodopsin ( RHO ) gene are the most common cause of autosomal dominant retinitis pigmentosa leading to photoreceptor degeneration. Quantitative imaging using adaptive optics (AO) revealed irregularities in cone organization, even in relatively...