Biff F. Palmer

Unlocking potassium secretion: the roles of aldosterone, ROMK, and WNK kinases in kidney potassium handling

The normal human kidney possesses a prodigious capacity to excrete dietary potassium (K+). This evolutionary adaptation is rooted in the high-K+ diets of prehistoric hominids, which are estimated to have reached 15,000 mg/day. Despite the progressive reduction in dietary K+ since...