Bernadien H. Jansen

Extended haplotypes at the complement factor H gene locus are associated with liver transplant rejection.

BACKGROUND: Acute T-cell-mediated rejection (ACR) remains an important complication after liver transplantation. Polymorphisms in the factor H gene (CFH) and factor H-related protein genes (CFHRs) affect the risk of multiple complement-related diseases. Given the complement syste...