Bart J. G. Broeckx

A homozygous hypomorphic FBN1 splice region variant in domestic cats with Marfan syndrome

Marfan syndrome (MFS) is an autosomal dominant connective tissue disease caused by variants in the fibrillin 1 ( FBN1 ) gene. While common in humans, spontaneous animal models are rarely reported. We present the first phenotypic and molecular characterization of MFS in domestic c...

Age‐dependent expression and heritability of owner‐reported dermatological symptoms in Labrador retrievers: Implications for breeding strategies

Objectives In decentralised breeding programmes, consistent health monitoring can be challenging, yet accurate phenotyping is essential for informed selection. This study evaluated whether a concise owner‐based online survey could capture clinically relevant dermatologic signs in...