Bart Ellenbroek

From Insulin Resistance to Mitochondrial Failure: A Staged Model of Impaired Metabolic Flexibility in Schizophrenia

Schizophrenia is a highly heritable neuropsychiatric disorder whose pathophysiology remains poorly understood. While neurotransmitter, neurodevelopmental, synaptic, and dysconnectivity hypotheses explain important aspects of the disorder, growing evidence suggests that metabolic...