Barbara Smolak

MALDI Mass Spectrometry Imaging in Alzheimer’s Disease Lipidomics: Matrix Selection, Spatial Lipid Pathology and Emerging Analytical Strategies

Alzheimer’s disease (AD) involves not only amyloid-β and tau pathology but also extensive disturbances in lipid metabolism, membrane organization, neuroinflammatory signaling, and tissue homeostasis. Conventional lipidomics has identified changes in phospholipids, sphingolipids,...