Balamurugan Shanmugaraj

Immunoinformatics-based design and in silico evaluation of a multi-epitope vaccine candidate against Naegleria fowleri

Primary amoebic meningoencephalitis (PAM) is caused by Naegleria fowleri , a free-living amoeba. It is a fatal infection with more than 95% mortality rate. Even though several combinations of antimicrobial agents were used to treat the condition, the overall survival remains poor...

Fusion Partner and ER-Retention Signal Are Associated with Distinct Host Proteomic and Metabolic Responses During Interleukin-15 Production in Nicotiana benthamiana

Plant molecular farming has emerged as a promising platform to produce recombinant biopharmaceuticals. The expression of foreign proteins changes the host proteome and metabolome, and these changes might have an effect on the accumulation of recombinant proteins. In this study, w...