Azeddine Ibrahimi

Integrative computational repositioning of Foretinib and PF-03715455 as potential GSTP1 inhibitors for cancer chemosensitization

Glutathione S-transferase P1 (GSTP1) plays a key role in tumor progression and drug detoxification, making it a promising target for reversing chemoresistance in cancer cells. Although several GSTP1 inhibitors have been identified, none have progressed to clinical use, mainly bec...