Author
Aysegül Ilhan‐Mutlu
Recent research
- Health & MedicineOpen access
Zanidatamab: reshaping the treatment landscape for HER2-positive gastroesophageal adenocarcinoma
Summary HER2 testing is essential in the pathological workup of metastatic gastroesophageal adenocarcinoma (GEA). Zanidatamab is a bispecific IgG1-like antibody that targets extracellular domains 2 and 4 of HER2 in a trans configuration. This biparotopic binding promotes receptor...