Ayan Majumder

Exploring the thermodynamic competition between APP C99 dimerization and membrane partitioning in model liquid-ordered and disordered membranes

Lateral membrane heterogeneity creates distinct lipid environments that modulate both the localization and association of transmembrane proteins. Previous studies have examined how transmembrane proteins partition between ordered and disordered domains, and separate studies have...

Structure and Dynamicsof the HIV-1 EnvelopeProtein on the Virion Envelope

HIV-1 buds from infected cells as immature virion particles with a scattered envelope glycoprotein (Env) distribution on their envelope. It then undergoes maturation, during which the viral protease cleaves the Gag polyprotein at multiple sites, leading to structural reorganizati...