Atsuhiro Ichihara

Association between serum soluble (pro)renin receptor level and lower limb amputation in hemodialysis patients

Abstract Background The (pro)renin receptor [(P)RR] is a multifunctional protein, and its soluble form [s(P)RR], generated by proteolytic cleavage, has been proposed as a biomarker reflecting tissue renin–angiotensin system activity. Patients on maintenance hemodialysis (HD) have...