Ashley Fisher

Airway protease availability governs a reversible shift between syncytial and cell-free spread

ABSTRACT Paramyxoviruses such as respiratory syncytial virus (RSV) and human parainfluenza virus 3 (HPIV3) spread in the airway by releasing virions and by forming syncytia. Spread phenotypes are typically attributed to the fusion protein cleavage site, yet it remains unclear whe...