Arjen M. Dondorp

Mass vaccination and drug administration for malaria elimination in Bangladesh: design and implementation of a community engagement strategy

Abstract Background Community engagement is increasingly recognised as an essential element of health research in underserved settings, yet limited evidence describes how engagement strategies are designed, adapted, and implemented during large-scale intervention trials. This imp...

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial

Abstract Mortality rates for African children with severe malaria remain high. Sevuparin, a heparin-like compound, as an adjunctive treatment, may improve outcomes due to its effects on Plasmodium falciparum -infected erythrocytes. A Phase I dose-finding trial in Kenyan and Zambi...