Aotian Guo

SOX2-OT potentiates E2F1-HES6 interaction to suppress natural killer cell activity and mediate immunosuppression in lung adenocarcinoma

Lung adenocarcinoma (LUAD) escapes immune surveillance by building an immunosuppressive tumor microenvironment. Within that microenvironment, impaired natural killer (NK) cell function is considered an important mechanism promoting tumor progression and immune escape. However, th...