Aohan Mei

Hierarchical Enzyme Function Prediction Based on Structural Confidence and Active-Site-Aware Attention

Accurate enzyme function prediction is important for protein functional annotation, drug discovery, metabolic-pathway analysis, and synthetic biology. Although recent structure-based methods have improved Enzyme Commission (EC) number prediction, they still have several limitatio...

Open-Set Semiconductor Defect Classification in SEM Images via Uncertainty-Aware Local Prototype Alignment

Automated classification of scanning electron microscope (SEM) defects is complicated by acquisition-domain shift, long-tailed classes, and target-only defect types that invalidate the closed-set assumption. We propose an offline open-set adaptation framework that combines a thre...