Antxon Martı́nez de Ilarduya

Copolymer Self-Assembly Triggered by Cis – Trans Polyproline Isomerization

Abstract Polyproline exists in two forms, the all-cis right-handed polyproline helix (type I) and the all-trans left-handed polyproline helix (type II). While the former is favored in common organic solvents, the latter is favored in aqueous solutions. Taking advantage of the hyd...

Poloxamer/HPMC/Carbopol-Based Thermosensitive Hydrogel Loaded with Ibuprofen for Potential Vaginal Drug Release

Vaginal drug delivery offers a critical route for local treatments but is limited by short formulation residence times. This study describes a thermosensitive in situ gel prepared by the cold-dissolution method from a ternary blend of Pluronic F127, Carbopol 940, and HPMC for loc...