Antonio Naranjo

Thermodynamic and structural paradigms of acetylcholinesterase inhibition: Mapping the superior stability of glucosylated eugenol analogues

Eugenol, a phenylpropene found predominantly in clove, is known for its neuroprotective effects, including the inhibition of human acetylcholinesterase (AChE). While early studies identified eugenols as an effective AChE inhibitor, the relative chemical space of its analogues rem...