Antonio Avallone

Systems serology identifies differential pan-viral seroreactivity profiles associated with healthy aging and cancer

Abstract A viral exposure signature (VES) has previously been shown to predict the development of hepatocellular carcinoma (HCC) in at-risk individuals through comprehensive serological profiling using the VirScan platform. Whether cumulative antimicrobial immune histories are as...

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...