Antonello Raponi

Capturing Thermal and Hydrodynamic Heterogeneity in Polymorphic Crystallization Scale-Up via Physics-Inspired Multicompartmental Population Balance Models

Abstract Scaling up crystallization processes is notoriously difficult for polymorphic systems, where spatial heterogeneities in temperature and hydrodynamics dictate nucleation, growth, agglomeration, and solid-form selection. Conventional population balance models (PBMs) genera...