Anouk Olthof

How to Establish a Reference Interval: A Practical Approach.

BACKGROUND: Establishing accurate reference intervals (RIs) is essential for interpreting clinical chemistry laboratory test results and ensuring clinical relevance. The aim of this review is to provide a practical guide to determine RIs using direct and indirect methods. CONTENT...

A literature overview of age- and Tanner stage-specific reference intervals for sex hormones for children aged 0 – 18 years

Abstract Study objective This study aims to provide a comprehensive overview of age- and Tanner stage-specific reference intervals (RIs) for testosterone, estradiol, luteinizing hormone (LH), follicle-stimulating hormone (FSH), and sex hormone-binding globulin (SHBG) in children...