Anne Kölsch

Serum p-tau181 and p-tau217 levels in adolescents and adults with 5q spinal muscular atrophy

Abstract Background Reliable blood biomarkers for longitudinal monitoring in adolescent and adult 5q spinal muscular atrophy (SMA) are lacking. Phosphorylated tau (p-tau) species are elevated in serum in amyotrophic lateral sclerosis (ALS), where they may reflect peripheral nerve...