Anna A. Karan

Delivery of transgenes into Gαo-rich subcortical structures of the mouse brain with potential applications for GNAO1 encephalopathy

Adeno-associated virus (AAV) vectors are widely used for transgene delivery into the mouse brain in preclinical studies, yet AAV methodology requires customization for each neurological disease. In this study, we aimed to identify the optimal approach for AAV-mediated transductio...