Ángel David García López

Expanding the Guanosine-Guanfacine Synergy: A Molecular Hypothesis Involving G-Quadruplex (G4) RNA Structures and Protein Phosphatase 2A (PP2A) in Neurodegeneration

Abstract Multitarget therapeutic strategies represent a critical shift in treating multifactorial neurodegenerative disorders like Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS). This hypothesis paper expands upon the previously proposed neuroprotective synergy...

Expanding the Guanosine-Guanfacine Synergy: A Molecular Hypothesis Involving G-Quadruplex (G4) RNA Structures and Protein Phosphatase 2A (PP2A) in Neurodegeneration

Abstract Multitarget therapeutic strategies represent a critical shift in treating multifactorial neurodegenerative disorders like Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS). This hypothesis paper expands upon the previously proposed neuroprotective synergy...