Andrey A. Smarygin

Learning is robust, seeing it is hard: attractor dynamics gate the readout of synaptic memory in a whole-brain spiking connectome model

No published work demonstrates reproducible associative learning inside a full connectome-constrained spiking model of the Drosophila brain; independent community attempts consistently report negative results. We show that the obstacle is not the learning rule but the readout. In...

Neurotransmitter sign and source-column errors in Drosophila connectome simulation pipelines: an audit of MaleCNS v1.0

Spiking simulations of the Drosophila connectome routinely assign each synapse an excitatory or inhibitory sign by mapping the neurotransmitter (NT) predicted for the presynaptic body to a polarity. Using the recently released MaleCNS v1.0 whole-central-nervous-system connectome...

Neurotransmitter sign and source-column errors in Drosophila connectome simulation pipelines: an audit of MaleCNS v1.0

Spiking simulations of the Drosophila connectome routinely assign each synapse an excitatory or inhibitory sign by mapping the neurotransmitter (NT) predicted for the presynaptic body to a polarity. Using the recently released MaleCNS v1.0 whole-central-nervous-system connectome...