Andrew Lai

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Ovarian cancer is the most lethal gynecological malignancy, due to late‐stage diagnosis, tumor heterogeneity, and lack of biomarkers for early detection. Extracellular vesicles (EVs) in plasma and ascites offer a minimally invasive source of tumor‐derived information, yet their l...

Salivary Extracellular Vesicles from Host, Bacteria and Fungus as Nanomessengers Reflecting Host−Microbiome Interaction in Periodontal Inflammation

Extracellular vesicles (EVs) secreted by the host and polymicrobial oral community are natural endogenous biological nanoparticles that mediate host-microbe interactions. Given their abundance in biofluids, host, fungal and bacterial EVs circulating in saliva may reflect periodon...