Andreas R. Winkel

Identification and binding-site mapping of RNA-binding proteins interacting with microRNA precursors in Arabidopsis

Abstract Background MicroRNAs (miRNAs) play key roles in modulating gene expression. Upon transcription, primary miRNA transcripts (pri-miRNAs or MIRNAs ) fold into stem-loop structures. Endonucleolytic cleavage releases a miRNA/miRNA* duplex from the stem, which is subsequently...