Andreas Gruber

Intratumoral desmoplastic stroma in carcinoma brain metastases harbors stromal cells with a cancer-associated fibroblast (CAF)-like immunophenotype

Abstract Background Research on the tumor microenvironment of brain metastases (BM) has largely focused on immune response, while the intratumoral stromal compartment remains poorly characterized. In primary carcinomas, cancer-associated fibroblast (CAF) are intratumoral stromal...