Author
Andrea L. Frump
Recent research
- Health & MedicineOpen access
Sexually Dimorphic Role of Estrogen Receptor α in Preserving Right Ventricular Endothelial Integrity
Abstract Right ventricular (RV) function and adaptation to afterload increase determine survival in pulmonary hypertension (PH). RV adaptation in PH is sexually dimorphic and more preserved in females, mediated by protective estrogen receptor α (ERα) signaling in cardiomyocytes....