Andrea Giovanni Ledda

Emerging therapeutic strategies and clinical trials in severe asthma management: current evidence and future directions

Introduction Biologic therapies have transformed the management of severe asthma, particularly in type 2-high disease, but important unmet needs remain. Incomplete responses, uncertainty in treatment positioning, and the lack of effective options for non-type 2 or mixed inflammat...

Rt-PCR detection of West Nile virus in rhino-pharyngeal swabs in patients with neuroinvasive WNV: a preliminary experience

Abstract West Nile virus (WNV) diagnosis relies on serology and/or RNA detection in serum or cerebrospinal fluid (CSF). However, lumbar puncture may be contraindicated in some patients, and serological diagnosis can be limited by impaired antibody responses or persistent IgM posi...