André D. J. McKenzie

Towards Improved P2X7R Cellular Models for Alzheimer’s Disease Drug Discovery

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with no disease-modifying therapeutics. The P2X7 receptor (P2X7R) presents as a promising target for AD drug discovery due to its pathogenic role in the onset and progression of neuroinflammation, a hal...