Ananya Dash

Diversity drives disease by Candida auris

The resilience of the emerging fungal pathogen Candida auris poses a significant challenge to public health. In a recent study examining how this pathogen navigates changing host environments, Tedja et al. show that sensing nutrient availability differences between body sites is...

Molecular basis and therapeutic potential of sortase A inhibitors as new antibiotics against MDR pathogens

Attaching proteins to the cell surface presents a technical challenge to Gram-positive bacteria. A class of enzymes called sortases solves this challenge by covalently anchoring proteins, including an arsenal of virulence factors, to the cell wall. Most Gram-positive bacteria hav...