Ana K. Herrera-Vargas

FAK regulates leptin-induced angiogenesis and vasculogenic mimicry in breast cancer

Abstract Leptin, an adipokine primarily secreted by adipose tissue, has been implicated in tumor progression by regulating angiogenesis. Leptin also plays a key role in tumor vascularization by promoting vasculogenic mimicry (VM). During tumor progression, leptin activates severa...