An Geng

Integrating single-cell RNA sequencing with Visium HD spatial atlas reveals immune–stromal cell interactions in Echinococcus multilocularis metacestode infection

Abstract Background Alveolar echinococcosis (AE), caused by the larval stage of the tapeworm Echinococcus multilocularis , is a fatal zoonotic disease characterized by progressive hepatic granulomatous inflammation and fibrosis. However, the mechanisms underlying the pathological...