An Dang Do

Aspiration and silent aspiration in Niemann-Pick disease type C1: longitudinal findings from the NIH natural history study

Abstract Background Niemann–Pick disease type C1 (NPC1) is a rare neurodegenerative disorder in which dysphagia is common and aspiration pneumonia is a leading cause of mortality. Aspiration may be clinically apparent or silent, reflecting impaired airway sensation and protective...