Amirrtavarshni Sivayoganathan

Endothelial neo-antigen expression initiates CD8⁺ T cell–driven CNS vasculitis amplified by peripheral immune challenge

Primary central nervous system (CNS) vasculitis is a rare and devastating inflammatory cerebrovascular disease for which pathogenic mechanisms remain poorly defined, largely due to limited access to human tissue and the absence of validated experimental models. Here, we present a...