Alicia Zhang

Engineering Bordetella pertussis BrkA Autotransporter for Chitin-Binding Domain Surface Expression: Exploring its Potential for Whole-Cell Immobilization

The BrkA autotransporter is an important virulence factor in Bordetella pertussis that confers serum resistance and mediates cell adherence. As it is self-secreting and only one protein needs to be manipulated, this makes it a relatively simple secretion pathway that can be explo...

Dopaminergic Therapeutics for Treating Parkinson’s Disease Were Associated with a Shift in the Gut Microbiota to Resemble Healthy Individuals

Parkinson’s Disease (PD) is a neurodegenerative disorder associated with dopaminergic neuron loss, leading to dopamine dysregulation. Dopaminergic therapeutics are often administered to restore dopamine levels and have been associated with changes to the gut microbiota. Through a...