Ali Fatehi Hassanabad

BET inhibitor apabetalone suppresses the fibrotic activation of cardiac fibroblasts associated with heart dysfunction

Background Accumulation of extracellular matrix (ECM) causes tissue fibrosis that contributes to myocardial dysfunction and heart failure (HF), yet there are no approved anti-fibrotic therapeutics that target it. Inhibitors of BET proteins (BETi) reduced fibrosis in preclinical H...

Deep learning-based segmentation of abdominal aortic aneurysm: a systematic review and meta-analysis of performance and clinical applicability

Abstract Background Abdominal aortic aneurysm (AAA) management relies heavily on imaging for surveillance, treatment planning, and follow-up. Deep learning (DL)-based segmentation may improve the efficiency and reproducibility of AAA image analysis; however, reported performance...