Alfonso Díaz

Early-life overconsumption of a high-carbohydrate diet induces metaflammation and kidney injury without impairment of function in adult Wistar rats

Abstract Frequent consumption of sugary and calorie-dense foods and beverages during childhood may contribute to the development of metabolic syndrome (MetS) in adulthood, a risk that can manifest independently of overweight status. Metaflammation, a low-grade inflammation associ...

Thromboxane A2-Driven Vascular Hyperreactivity in Cadmium-Induced Hypertension: Role of Oxidative Stress and Therapeutic Implications

Background/Objectives: Environmental factors, including heavy metals such as cadmium, are increasingly recognized as important contributors to hypertension beyond traditional risk factors. To date, the role of angiotensin and alpha-adrenergic receptors in hypertension induced by...