Alexandru Cărăuleanu

Deep-Learning-Based Assessment of Breast Arterial Calcification on Mammography: Technical Validation, Cardiovascular Prognostic Value, and Clinical Translation—A Narrative Review

Breast arterial calcification (BAC) is a manifestation of medial arterial calcification frequently detected incidentally on screening mammography. Increasing evidence suggests that BAC may also serve as a marker of cardiovascular risk. This narrative review critically synthesizes...

From Active Compound to Target Epithelium: Local Delivery, Preclinical Model Validity, and Clinical Endpoint Interpretation in Topical Therapy for HPV-Associated Lower Genital Tract Disease—A Narrative Review

Cervical excision increases the risk of preterm birth, while active surveillance for grade 2 cervical intraepithelial neoplasia offers no active treatment. Topical therapy for human papillomavirus (HPV)-associated lower genital tract disease could address this gap, yet no agent i...

Maternal Cardiovascular Phenotype in Fetal Growth Restriction with or Without Pre-Eclampsia: Insights from Echocardiography and Clinical Implications

Fetal growth restriction (FGR) has traditionally been attributed to placental insufficiency. However, accumulating evidence suggests that maternal cardiovascular maladaptation contributes to disease expression, clinical heterogeneity, and long-term maternal cardiovascular risk. T...