Alexandr Ignatchenko

α-Latrotoxin and Pain: A Nociceptor Perspective on Latrodectism

Alpha-latrotoxin (α-LTX) is the principal vertebrate-specific neurotoxin in widow spider (Latrodectus) venom and a powerful presynaptic secretagogue. Although its receptors, pore-forming activity and stimulation of neurotransmitter release have been studied extensively in central...