Alex Wardale

lncOriL, a polyadenylated mitochondrial lncRNA common to zebrafish and human

Abstract Background Even though teleost fish and mammals share the same mitochondrial gene content and organization, the teleost mitochondrial transcriptome is still poorly understood. Here we characterized the mitochondrial transcriptome during zebrafish ( Danio rerio ) early de...

Single-nucleotide resolution mapping of m6A in zebrafish early embryonic development identifies developmental stage-associated modification dynamics during the maternal-to-zygotic transition

Abstract N 6 -methyladenosine (m 6 A) is the most abundant epigenetic modification on eukaryotic mRNA and has important roles in gene expression. While m 6 A distribution and localization have been defined in zebrafish using antibody-based methods, no research has been published...