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Gut-selective integrin-targeted therapy improves metabolic pathways in the early immune activation mouse model of autism spectrum disorder as revealed by untargeted metabolomics

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology, often associated with gastrointestinal dysfunction and immune dysregulation. The microbiota-gut-brain axis is emerging as a crucial pathway in ASD pathogenesis, mediating the communication betw...