Aleksandra Markiewicz

Mitochondrial transcript abundance in breast cancer circulating tumour cells may reflect both blood-derived transcripts and biological heterogeneity

Circulating tumour cells (CTCs) are rare cells frequently profiled on a single cell level. A key indicator of single-cell transcriptome quality is the percentage of reads encoded by genes in the mitochondrial genome (MT-reads). No systematic data exists on MT-reads content in CTC...