Author
Aleksandar Sič
Recent research
- BiologyOpen access
Targeting MicroRNA-21 in Chronic Kidney Disease: Lessons from the Lademirsen Story
MicroRNA-21 (miR-21) has long been regarded as one of the most promising molecular targets in chronic kidney disease (CKD) because of its consistent upregulation across diverse renal disorders and its involvement in fibrosis, inflammation, oxidative stress, and metabolic dysfunct...
- BiologyOpen access
Chronic pain, sleep disturbances, and mental health disorders such as anxiety and depression disorders frequently co-occur, forming a self-reinforcing cycle that impairs daily functioning and quality of life. Chronic pain is driven by peripheral and central sensitization, the lat...