Alejandro Sifrim

LIPOGRID: A HIGH-THROUGHPUT MULTI-OMICS PERTURBATION SCREEN DISSECTS THE GENETIC ARCHITECTURE OF LIPID METABOLISM

Lipids constitute one of the largest and most diverse classes of cellular molecules, sustaining membrane architecture, energy storage, and signaling. Consequently, their dysregulation underlies a broad spectrum of human disease. However, the genetic mechanisms governing lipid hom...