Alcides J. M. da Silva

Novel Synthetic Chalcones Display Potent Anti- Leishmania ( Viannia ) braziliensis Profile and Inhibit Proteolytic Activities

Abstract American Tegumentary Leishmaniasis, primarily caused by Leishmania (Viannia) braziliensis, remains a major public health challenge in Latin America. The variable efficacy and toxicity of pentavalent antimonials underscore the urgent need for new therapeutic candidates. A...