Albert SW Sohn

Differential regulation of the proliferative and autophagic responses in murine and human pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) cells rely on autophagy to adapt to microenvironmental stress. In our recent work, we showed that baseline autophagy flux levels shape the proliferative capacity of human PDAC cells. Here, we extend these findings by demonstrating that low...