Akira Nagahara

Clinical efficacy and safety of second-line cabozantinib after first-line immune checkpoint inhibitor-based combinations in metastatic renal cell carcinoma: a multicenter retrospective study

Abstract Background The efficacy of second-line cabozantinib following first-line immune checkpoint inhibitor (ICI)-based combinations, particularly after pembrolizumab plus lenvatinib (Pem + Len), remains uncharacterized. We evaluated real-world outcomes in patients with metasta...

Reproducibility of a quantitative body diffusion score derived from whole-body diffusion-weighted imaging (DWIBS) for assessment of bone metastases in prostate cancer

Abstract Purpose To evaluate whether changes in diffusion-based total lesion volume (ΔtDV) on whole-body MRI correlate with changes in serum prostate-specific antigen (ΔPSA) after therapy, and to assess reproducibility of ΔtDV measurements. Materials and Methods This retrospectiv...