Ajal K. Prakash

Biotin-Functionalized Multi-Stimuli-Responsive Polymeric Prodrug for Receptor-Mediated and Mitochondria-Targeted Codelivery of Camptothecin and Protocatechualdehyde

Abstract Triple-negative breast cancer (TNBC) remains difficult to treat because of limited molecular targets and multidrug resistance. Here, we develop CPB, a biodegradable poly(ε-caprolactone)-polymeric prodrug nanoplatform integrating biotin-mediated uptake, triphenylphosphoni...